There is a launch of norepinephrine within the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors in the dorsal horn to decrease afferent pain transmission and produce analgesia. As a result, medications like clonidine that focus on alpha-2 receptors can impact the transmission of soreness. Jun ten, 2024 · https://grahamd802yri2.wikiconversation.com/user