In this article, we present that conolidine, a pure analgesic alkaloid used in standard Chinese medication, targets ACKR3, therefore providing added evidence of a correlation concerning ACKR3 and soreness modulation and opening alternate therapeutic avenues with the cure of chronic pain. Tabernaemontana divaricata Conolidine is really an indole alkaloid. https://timociw059trt0.wikigiogio.com/user