PB-22 and 5F-PB-22 were the 1st synthetic cannabinoids to incorporate a quinoline substructure and an ester linkage. These compounds are assumed to happen to be synthesized Using the intention of setting up a synthetic cannabinoid prodrug, which could reinforce absorption and confound detection. A concept from Culture Editor Jennifer Goldberg: https://ralphd047fqa5.wikihearsay.com/user